Manager, Research & Development (Upstream, Cell culture expert)
Thermo Fisher Scientific, Inc.
Marsiling, Singapore
5d ago

Job Description

R&D Manager (Upstream, Cell culture expert)

What will you do?

  • Develop and optimize cell culture media and processes suitable for manufacture and meeting customer requirements for large scale production of recombinant proteins
  • Maximize potential for successful scale-up manufacturing and technology transfer
  • Ensure new media satisfy project goals
  • Understand product development processes; able to lead product development teams
  • Support upstream cell culture operations
  • Lead a media development team developing media formulations for customer cell lines
  • Adhere to EHS standards and complies with Thermo Fisher Scientific laboratory quality systems
  • Rotational week end work will be expected
  • I. Education

  • A PhD degree with relevant work experience.
  • Essential Criteria

  • Minimum of 8-10 years’ experience in bio / pharma industry in the area of mammalian cell culture (CHO)
  • Demonstrated significant accomplishments leading cross-functional technology and product development teams
  • Scale-up manufacturing, technology transfer, and record of successful accomplishment on cross-functional teams
  • Participation on successful product development teams
  • Must have extensive and technical expertise relating to mammalian cell culture, media development and cell culture process development disciplines
  • Understands new scientific concepts and ideas
  • Aptitude for statistical analysis and experimental design
  • Excellent grasp of sterile techniques
  • Excellent organizational skills, including the ability to efficiently evaluate, and prioritize multiple and changing priorities
  • Able to work independently.
  • III. Knowledge, Skills, Abilities

  • Strong written, verbal. and presentation skills
  • Able to supervise multiple technical teams and subordinates who exercise considerable independence
  • Ability to interact effectively with customers
  • Experience in statistical media design software (DesignExpert)
  • Experience in high-throughput small-scale cell culture systems eg.deepwell plates and spin-tubes and AMBR microbioreactor system
  • Experience with Sartorius bench scale bioreactor systems and ATF systems
  • Apply
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